Slow Release Melatonin: The Answer You’re Looking For

Slow Release Melatonin: The Answer You’re Looking For

Do you have problems falling asleep at night, or wake up during the night feeling as if you have an adrenalin rush, or with a panic attack, or even due to nightmares? These could be symptoms of neurotransmitter dysregulation. The quickest way to help you out of this predicament may be slow release melatonin.

But, this still leaves certain questions unanswered, such as why is this happening to me, what is neurotransmitter dysregulation, and what does slow release melatonin have to do with it?

Neurotransmitter Dysregulation

Regulation of sleep, in our body, can be greatly affected by neurotransmitters and hormones. These are brain chemicals that regulate the distribution of every thought process and control signal that is processed by the brain, and then forward them on to different glands, organs, nerves, etc. In other words, they tell your stomach to secrete digestive juices, your liver to detoxify the body, the adrenal glands to produce and secrete the hormones necessary to either fight or flee, and the heart to pump blood.

These neurotransmitters include the following hormones:

  • Serotonin: Helps to regulate your sleep cycle, helps the body process pain and plays a role in mood, body temperature, appetite, and your sex drive. It is also a precursor hormone for melatonin, which is needed to sleep.
  • Norepinephrine (noradrenaline): Helps keep you alert and boosts your memory. It is also involved in the “fight or flight response” when your body feels it is under threat.
  • Dopamine: Helps make you ‘feel good’ when you have done something well. It also assists with focusing.
  • Other neurotransmitters include Glutamate, which stimulates the brain for learning and gamma-Aminobutyric acid (GABA) that calms you and keeps you relaxed.

When, for any reason, the proper functioning of these neurotransmitters is compromised, especially slow-release melatonin, the sleep hormone, your sleep pattern is compromised as well. One of the main reasons for the dysregulation of your neurotransmitters is adrenal fatigue:

Conditions Associated with Neurotransmitter Dysregulation

There are a number of symptoms that those, who have this problem, encounter. The majority are also related to adrenal fatigue. They include:

  • Sleep disorders/insomnia
  • Anxiety/panic attacks
  • Depression/moodiness
  • Eating disorders, e.g. bulimia, anorexia, obesity
  • Migraines/headaches
  • Chronic pain
  • Restless legs syndrome
  • PMS
  • Hypoglycemia
  • Fibromyalgia

Common Causes of Neurotransmitter Dysregulation

The causes of each person’s dysregulation may be different or due to more than one factor. The most common factors include:


One needs a balanced diet containing the vitamins, minerals, and amino acids needed by the body in order to create the necessary neurotransmitters in order to function optimally. Where diet is lacking, an imbalance usually follows, compromising, amongst other things, your sleep patterns.

Stimulants and slow release melatonin


Stimulants derived from coffee, chocolate, and certain medications have an adverse effect on your neurotransmitters as they create a resistance to it. Selected glandular and herbs also can have stimulatory properties, including licorice, ashwagandha, maca, and green tea.


Many medications deplete your body’s serotonin/melatonin levels. Many of these medications are specifically prescribed to increase the brain’s levels of serotonin/melatonin, but in the long run, have the opposite effect. This is because, as the brain’s levels of these hormones are increased, the body works harder at metabolizing them, causing a further decrease.


Lifestyle plays a huge role with regards to the production of your brain’s melatonin. Due to the fast-paced life we live today as compared to our great-grandparents, we are increasingly exposed to higher levels of stress and overworked. Stress plays an important role in melatonin production, while it has a huge effect on the general production of hormones throughout the body, most noticeably, at first, in the adrenal glands and brain.

Too much external stimuli

We are constantly bombarded by visual and auditory stimuli. It is everywhere around us, from motorcars to television, to a radio, to radio waves, to fluorescent lights. We cannot, in the world we live in today, get away from it. These stimuli are constantly bombarding our senses, keeping us stimulated, and in doing so, compromising the production of melatonin, the hormone needed for sleep.

The gastrointestinal tract

The gastrointestinal tract is one of the largest sources of neurotransmitter precursors. When it is compromised, it, in turn, compromises the production and thus the functioning of your body’s neurotransmitters. Common causes for a decline in this type of functionality includes intestinal permeability (also commonly referred to as leaky gut), Candida, and inflammatory bowel, amongst others.

Adrenal fatigue

Serotonin is the precursor of melatonin, which is primarily a sleep-inducing hormone. When your melatonin levels are compromised, disturbed sleep, difficulties with falling asleep, and other such issues such as nightmares, as an example, are often the result.

People who have these problems, especially those in the various stages of adrenal fatigue syndrome, usually have an imbalance with regards to their melatonin/cortisol levels. This imbalance plays a very large role with regards to their problem at hand.

Adrenal Function and Melatonin

Excessive amounts of cortisol have a negative influence on your melatonin production, while lowered levels of melatonin production, for whatever reason, causes your cortisol levels to disrupt your sleep pattern.

One of the ways in which your melatonin production is hampered is due to too much light. Slow-release melatonin needs darker conditions in order to be produced. When less melatonin is produced, it skewers things in the favor of cortisol, which keeps the body alert and ready for action. The overproduction of cortisol due to various reasons, however, has the same effect.

When the body is put under stress, the hypothalamus in the brain sends chemical messages to the pituitary gland informing it of this. In turn, the pituitary gland sends messages to the adrenal glands, causing them to produce more cortisol to keep the body ready to either fight or flee from the perceived threatening situation. Neurological functions and slow release melatoninDuring this process, other functions, deemed non-essential for life, are either limited or stopped. Once the threat is over, the brain signals as much to the pituitary gland that in turn sends out its ‘all clear’ signal and normal functionality is returned. This is the body’s normal response to any stressful situation, whether it is physical, psychological, or environmental in nature.

The hypothalamus, pituitary gland, and adrenal glands are commonly referred to as the HPA-axis and are part of the endocrine system – a collection of glands throughout the body responsible for the production of the hormones that regulate your metabolism, sexual function, growth and development, and a host of others browse around here.